Antibacterial Activity of Coumarine Derivatives Synthesized from 4-Chloro-chromen-2-one. The Comparison with Standard Drug.
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چکیده
منابع مشابه
6-Chloro-4-(4-methylphenoxymethyl)-2H-chromen-2-one
In the title compound, C(17)H(13)ClO(3), the coumarin and phen-oxy moieties are essentially co-planar, making a dihedral angle of 1.99 (7)°. The phen-oxy moiety is oriented anti-periplanar with respect to the coumarin ring as indicated by the C-C-O-C angle of -179.97 (16)°. In the crystal, the sheet-like packing is stabilized by inter-molecular C-H⋯O and C-H⋯Cl hydrogen bonds.
متن کامل2-(4-Methylphenyl)-7-(2-methylpropoxy)-4H-chromen-4-one–6-chloro-2-(4-methylphenyl)-7-(2-methylpropoxy)-4H-chromen-4-one (19/1)
The title co-crystal, 0.95C(20)H(20)O(3)·0.05C(20)H(19)ClO(3), arises as the chloride carried over during the synthesis shares a position with an aromatic H atom; the partial occupancies are 0.947 (2) and 0.053 (2) for H and Cl, respectively. The mol-ecular structure is stabilized by intra-molecular C-H⋯O contacts, forming pseudo five- and six-membered rings with S(5) and S(6) graph-set motifs,...
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Several new 2-pyridyl-4-thiazolidinones are synthesized in an efficient manner evading using any catalyst or base. Simple workup procedure, good yields, and mild reaction conditions are the salient features of this method. All the synthesized compounds are screened for antimicrobial activity against several organisms.
متن کامل2-(4-Chlorophenyl)chromen-4-one
The title compound, C(15)H(9)ClO(2), is a synthetic flavonoid obtained by the cyclization of 3-(4-chloro-phen-yl)-1-(2-hy-droxy-phen-yl)prop-2-en-1-one. The 4-chloro-phenyl ring is twisted at an angle of 11.54° with respect to the chromen-4-one skeleton. In the crystal, pairs of mol-ecules are inter-connected by weak Cl⋯Cl inter-actions [3.3089 (10) Å] forming dimmers which are further peripher...
متن کامل3-(2-Amino-1,3-thiazol-4-yl)-6-chloro-2H-chromen-2-one
The title compound, C(12)H(7)ClN(2)O(2)S, crystallizes with two mol-ecules in the asymmetric unit. The mol-ecular conformation is roughly planar for both these mol-ecules with maximum deviations of 0.177 (3) and 0.076 (4) Å from their respective mean planes. In the crystal, strong N-H⋯N and weak but highly directional C-H⋯O hydrogen bonds provide the links between the mol-ecules. The structure ...
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ژورنال
عنوان ژورنال: Oriental Journal of Chemistry
سال: 2014
ISSN: 0970-020X,2231-5039
DOI: 10.13005/ojc/300433